Continuous manufacturing builds on synthetic and analytical chemistry fundamentals, engineered to efficiently progress through the manufacturing process in integrated steps using sequential flow unit operations.
Manufacturing “in flow” allows for efficient processing of material at a much smaller scale, eliminating the need for large and expensive batch reactors in even larger facilities. With a smaller footprint and integrated process analytics, high quality material is produced in less time with less waste.
Furthermore, continuous manufacturing enables a fully integrated US based supply chain, with rapid response times, eliminating the need for large inventory hold points and potential supply chain breaks existing in today’s batch-oriented manufacturing approach. Get in touch with a Continuity Pharma professional to learn more!
Investing in continuous manufacturing for generic drug products with single suppliers, supply chain issues, or recent market shortages offers several major advantages.
Reduce supply chain risk
Continuous manufacturing integrates multi-step manufacturing processes into a single site, allowing self-sufficient manufacturing capability within the US. This reduces our dependence on generic drug supply from China, India and other off-shore supply chain nodes.
Number up to scale up
Continuous manufacturing operates in a small footprint, with refrigerator-size production units. Rather than scaling to larger equipment and even larger facilities, continuous manufacturing is scaled by adding manufacturing lines at the same scale. By scaling out, rather than up, strategic choices on location can enable rapid response and business continuity in times of pandemic or natural disaster.
Design for on demand production
Supply chain demand can change dramatically in the event of natural disaster, epidemic, or humanitarian need. With a fully integrated process and small footprint, continuous manufacturing capability can be rapidly deployed to where the drug supply is needed.
Improved operational and environmental safety
With the targeted design of environmentally safer reactions, coupled with the advantage of smaller scale operations, continuous manufacturing provides improved operational and environmental safety for the production of essential medicines.
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